They say that your golden years are the best years of your life. For most older Americans, that's how it should be - a time to relax, reflect, and live life in a familiar place. After all, senior citizens in the U.S. have worked tirelessly to build a better economy, serve their communities, and raise families.
However, as seniors grow older, sometimes they cannot live independently without someone by their side to provide care. Unfortunately, some older Americans aren't able to rely on their adult children for help. The reality in today's world is that family members do not have the skills or time to dedicate to caring for their parents. That's where Always Best Care Senior Services comes in.
Our in-home care services are for people who prefer to stay at home as they grow older but need ongoing care that family or friends cannot provide. More and more older adults prefer to live in the comforts or their home rather than in an assisted living community. Home care in Virgin, UT is a safe, effective way to give your loved ones the care they need when they need it the most.
Since 1996, Always Best Care has provided non-medical in-home care for seniors to help them maintain a healthy lifestyle as they age. We are proud to have helped tens of thousands of seniors to maintain a higher level of dignity and respect. We focus on providing seniors with the highest level of home care available so that they may live happily and independently.
Unlike some senior care companies, we genuinely want to be included in our clients' lives. We believe that personalized care is always the better option over a "one size fits all" approach. To make sure our senior clients receive the best care possible, we pair them with compassionate caregivers who understand their unique needs.
The Always Best Care difference lies in life's little moments - where compassionate care and trustworthy experience come together to help seniors live a fruitful, healthy life. Whether you are an aging adult that can't quite keep up with life's daily tasks or the child of a senior who needs regular in-home care services in Virgin, UT. Always Best Care is here to help.
Home is where the heart is. While that saying can sound a tad cliche, it's especially true for many seniors living in America. When given a choice, older adults most often prefer to grow older at home. An AARP study found that three out of four adults over the age of 50 want to stay in their homes and communities as they age. When you begin to think about why, it makes sense. Home offers a sense of security, comfort, and familiarity.
The truth is, as we age, we begin to rely on others for help. When a family is too busy or lives too far away to fulfill this role, in-home senior care is often the best solution. Home care services allow seniors to enjoy personal independence while also receiving trustworthy assistance from a trained caregiver.
At Always Best Care, we offer a comprehensive range of home care services to help seniors stay healthy while they get the help they need to remain independent. As your senior loved one ages, giving them the gift of senior care is one of the best ways to show your love, even if you live far away.
To give our senior clients the best care possible, we offer a full spectrum of in-home care services:
If your senior loved one has specific care needs, our personal care services are a great choice to consider. Personal care includes the standard caregiving duties associated with companion care and includes help with tasks such as dressing and grooming. Personal care can also help individuals with chronic conditions like diabetes or Parkinson's or Alzheimer's.
Sometimes, seniors need helpful reminders to maintain a high quality of life at home. If you or your senior has trouble with everyday tasks like cooking, our home helper services will be very beneficial.
Using this kind of care is a fantastic way to make life easier for you or your senior loved one. At Always Best Care, our talented caregivers often fill the role of a companion for seniors. That way, older adults can enjoy their favorite activities and hobbies while also receiving the care they need daily or weekly.
According to AARP, more than 53 million adults living in the U.S. provide care to someone over 50 years old. Unfortunately, these caregivers experience stress, exhaustion, and even depression. Our respite care services help family caregivers address urgent obligations, spend time with their children, and enjoy other activities. Perhaps more importantly, respite care gives family members time to recharge and regroup. Taking personal time to de-stress helps reduce the risks of caregiver burnout.
When it comes to non-medical home care, our goal is to become a valuable part of your senior's daily routine. That way, we may help give them the highest quality of life possible. We know that staying at home is important for your loved one, and we are here to help make sure that is possible. If you have been on the fence about non-medical home care, there has never been a better time than now to give your senior the care, assistance, and companionship they deserve.
Always Best Care in-home services are for older adults who prefer to stay at home but need ongoing care that friends and family cannot provide. In-home care is a safe, effective way for seniors to age gracefully in a familiar place and live independent, non-institutionalized lives. The benefits of non-medical home care are numerous. Here are just a few reasons to consider senior care services from Always Best Care:
While it's true that some seniors have complicated medical needs that prevent them from staying at home, aging in place is often the best arrangement for seniors and their families. With a trusted caregiver, seniors have the opportunity to live with a sense of dignity and do so as they see fit.
In-home care makes it possible for millions of seniors to age in place every year. Rather than moving to a unfamiliar assisted living community, seniors have the chance to stay at home where they feel the happiest and most comfortable.
How much does a senior's home truly mean to them?
A study published by the American Society on Aging found that more than half of seniors say their home's emotional value means more than how much their home is worth in monetary value. It stands to reason, that a senior's home is where they want to grow old. With the help of elderly care in Virgin, UT, seniors don't have to age in a sterilized care facility. Instead, they can age gracefully in the place they want to be most: their home. In contrast, seniors who move to a long-term care facility must adapt to new environments, new people, and new systems that the facility implements. At this stage in life, this kind of drastic change can be more harmful than helpful.
Institutional care facilities like nursing homes often put large groups of people together to live in one location. On any given day, dozens of staff members and caregivers run in and out of these facilities. Being around so many new people in a relatively small living environment can be dangerous for a seniors' health and wellbeing. When you consider that thousands of seniors passed away in nursing homes during the COVID-19 pandemic, opting for in-home care is often a safer, healthier choice for seniors. Aging in place has been shown to improve seniors' quality of life, which helps boost physical health and also helps insulate them from viral and bacterial risks found in elderly living facilities.
For many seniors, the ability to live independently with assistance from a caregiver is a priceless option. With in-home care, seniors experience a higher level of independence and freedom - much more so than in other settings like an assisted living community. When a senior has the chance to age in place, they get to live life on their own terms, inside the house that they helped make into a home. More independence means more control over their personal lives, too, which leads to increased levels of fulfillment, happiness, and personal gratification. Over time, these positive feelings can manifest into a healthier, longer life.
More independence, a healthier life, and increased comfort are only a few benefits of aging in place. You have to take into consideration the role of cost and convenience. Simply put, it's usually easier to help seniors age in place than it is to move them into an institutional care facility. In-home care services from Always Best Care, for instance, can be less expensive than long-term solutions, which can cost upwards of six figures per year. To make matters worse, many residential care facilities are reluctant to accept long-term care insurance and other types of payment assistance.
With Always Best Care's home care services, seniors and their families have a greater level of control over their care plans. In-home care in Virgin, UT gives seniors the chance to form a bond with a trusted caregiver and also receive unmatched care that is catered to their needs. In long-term care facilities, seniors and their loved ones have much less control over their care plan and have less of a say in who provides their care.
In-home care is a valuable resource that empowers seniors to age in place on their own terms. However, a big concern for many families and their loved ones is how much in-home care costs. If you're worried that in-home care is too expensive, you may be pleasantly surprised to learn that it is one of the most affordable senior care arrangements available.
Typically, hiring an Always Best Care in-home caregiver for a few hours a week is more affordable than sending your loved one to a long-term care facility. This is true even for seniors with more complex care needs.
At Always Best Care, we will work closely with you and your family to develop a Care Plan that not only meets your care needs, but your budget requirements, too. Once we discover the level of care that you or your senior need, we develop an in-home care plan that you can afford.
When you or your senior loved one needs assistance managing daily tasks at home, finding a qualified caregiver can be challenging. It takes a special kind of person to provide reliable care for your senior loved one. However, a caregiver's role involves more than meal preparation and medication reminders. Many seniors rely on their caregivers for companionship, too.
Our companion care services give seniors the chance to socialize in a safe environment and engage in activities at home. These important efforts boost morale and provide much-needed relief from repetitive daily routines. A one-on-one, engaging conversation can sharpen seniors' minds and give them something in which to be excited.
At Always Best Care, we only hire care providers that we would trust to care for our own loved ones. Our senior caregivers in Virgin,UT understand how important it is to listen and communicate with their seniors. A seemingly small interaction, like a short hug goodbye, can make a major difference in a senior's day. Instead of battling against feelings of isolation, seniors begin to look forward to seeing their caregiver each week.
Understanding the nuances of senior care is just one of the reasons why our care providers are so great at their job.
Unlike some senior care companies, our caregivers must undergo extensive training before they work for Always Best Care. In addition, our caregivers receive ongoing training throughout the year. This training ensures that their standard of care matches up to the high standards we've come to expect. During this training, they will brush up on their communication skills, safety awareness, and symptom spotting. That way, your loved one receives the highest level of non-medical home care from day one.
The first step in getting quality in-home care starts with a personal consultation with an experienced Care Coordinator. This initial consultation is crucial for our team to learn more about you or your elderly loved one to discover the level of care required. Topics of this consultation typically include:
An assessment of your senior loved one
An in-depth discussion of the needs of your senior loved one to remain in their own home
Reviewing a detailed Care Plan that will meet your senior loved one's needs
Cedar City may be a small city in Utah, but it has a lot to offer visitors. For starters, it is within a few hours' drive of several natural parks in Utah, Nevada, Arizona, and even California. In fact, the famous Grand Canyon National Park can be a day trip from Cedar City and Zion National Park is just an hour's drive away. This is not to mention ...
Cedar City may be a small city in Utah, but it has a lot to offer visitors. For starters, it is within a few hours' drive of several natural parks in Utah, Nevada, Arizona, and even California. In fact, the famous Grand Canyon National Park can be a day trip from Cedar City and Zion National Park is just an hour's drive away. This is not to mention Utah's 5 other National Parks, which are accessible from Cedar City. This is why this destination is regarded as a gateway to the area's national parks.
However, Cedar City doesn't just send visitors away to the natural sights, it also offers a wealth of things to do that keep them busy throughout their stay. Granted, this is an outdoorsy destination, so a lot of the activities here involve hiking, mountain biking, and snow sports in winter. Still, this destination offers a lot to lovers of festivals as it hosts dozens of these in the warmer months, earning it the moniker Festival City. For those who want to visit, this ultimate travel guide to Cedar City has helpful information that a traveler would need when planning a trip to this Southern Utah city.
Since Cedar City is a destination for lovers of the outdoors, the best time to visit is when the weather supports outdoor activities. April to September have the best weather, making these months good times to visit Cedar City.
It gets really hot in summer (June to August) with temperatures peaking at around 90 degrees Fahrenheit (32 degrees Celsius).
Temperatures in April and May are milder, averaging 70 degrees Fahrenheit (20 degrees Celsius).
However, late spring and summer are peak travel times in Cedar City, so there are more crowds at the attractions.
Fall (September to November) is also an excellent time to travel since the heat of summer has started dissipating, but the weather remains pleasant. Granted, it might feel cold as winter approaches.
Temperatures at this time have an average range of 64 degrees Fahrenheit (18 degrees Celsius) to 40 degrees Fahrenheit (4 degrees Celsius).
Lovers of winter sports can visit Cedar City between December and February. Temperatures can drop to as low as 20 degrees Fahrenheit (-6 degrees Celsius). Still, there is a lot to do in winter in Utah.
Tip: Fall is a good time to visit Cedar City for those who want fewer crowds and lower hotel and flight rates.
Cedar City has a public bus system run by the Cedar Area Transportation Department. The buses only operate on weekdays from 7 am to 6 pm.
There are many sights to visit in and around Cedar City, so having a car makes it easier to explore all these attractions.
Car rental services like Enterprise Rent-A-Car, Avis, and Budget Car Rental are found in the city.
Traditional taxi companies like Iron County Taxi and Soul Taxi are found in Cedar City. Visitors can also use cab-hailing services like Uber and Lyft.
The Grind is a modest coffee shop in the heart of Cedar City. Their specialty is coffee, from mocha to café au lait, and many more. However, their breakfast sandwiches are also beloved among locals and visitors.
Options include a Dr. Seuss-inspired Green Eggs and Ham Sandwich, Rise and Shine Sandwich (eggs, chilies, onions, and tomatoes), and the All Day Breakfast Sandwich.
Their breakfast menu also includes waffles, bagels, and oatmeal.
How about some Pizza for lunch? Centro Woodfired Pizzeria is the place to go when the pizza cravings strike while in Cedar City. This charming little restaurant has a variety of starters, salads, and desserts, but the main draw is its pizzas.
Options include Fennel Sausage, Centro Italiano, Pollo Rustico, and Pollo Bianco. Centro is recognized as the best pizza restaurant in Cedar City with accolades from past customers.
This restaurant’s rustic theme harkens back to Utah’s Wild West history with a ranch-style design. This adds to the charm of Rusty’s Ranch House that’s then complemented by the good food.
Rusty’s serves different steak options as well as BBQ treats like Baby Back Ribs. They also have seafood, with fresh salmon and coconut shrimp as the main choices.
Customers can also order pasta, burgers, and desserts like apple cobbler.
One of the best places to enjoy a drink until late in Cedar City is Warehouse Bar. This establishment has a cheerful vibe that gives its patrons a memorable nightlife experience. Food is served here, with options like Deviled Eggs, Beef Sliders, Fish + Chips, and Pulled Pork Sliders.
Plus, the drinks make Warehouse Bar popular; they sell both draft and bottled beer and a variety of cocktails.
Cedar City is known as the Festival City because it hosts festivals almost throughout the year. Visitors who drop by in the warmer months can attend festivals like the Utah Midsummer Renaissance Fair, the Wildflower Festival, or the famous Utah Shakespeare Festival.
Other festivals include the Utah UFO Festival, Red Rock Film Festival, and Cedar Livestock & Heritage Festival.
Dixie National Forest is about 50 miles from Cedar City, a drive that lasts about an hour. This site is home to diverse natural features like canyon gorges, mountain forests, and alpine lakes. All these make for breathtaking scenery that’s a testament to Utah’s beauty.
Visitors can hike the miles upon miles of trails that go past juniper forests, wildflower meadows, and red rock canyons.
There are also campsites for tents and RV camping, as well as cabins rentals. Dixie is also a popular skiing and snowboarding site in winter.
Frontier Homestead State Park is an 11-acre park and museum, which showcases the history of the county from its iron-mining past to the present day.
The museum section has exhibits from the late 1800s to the early 1900s, including horse-drawn carriages and Native American artifacts. The park has hiking and biking trails and picnic spots.
This US National Monument is found about 23 miles from Cedar City. The site is a 3-mile natural amphitheater that rises to 10,000 feet above sea level. Visitors who hike to the top are rewarded with spectacular views of the multicolored canyon. There are trails that stretch for about 2 miles, two of which can be accessed from the road.
Cedar Breaks also hosts skiing and snowmobiling enthusiasts in the winter.
Lake at the Hills is an artificial lake in Cedar City that has its own beach. Visitors can rent kayaks here for a thrill in the water. There’s also a boat ramp for launching non-motorized boats.
The lake is also home to fish like catfish, bass, rainbow trout, and albino trout.
Fishing is allowed, but there’s a limit of just two per person, per day.
Cedar City is at least an hour's drive to Utah's national parks and one in Arizona. Here's a look at the national parks within four hours of Cedar City.
This national park is about 60 miles south of Cedar City, a journey that takes just an hour. The park is home to the Virgin River, Timber Creek, Kolob Canyons, and Zion Canyon. Visitors can take one of the 16 trails to get a view of the park's natural sights.
Located about 70 miles from Cedar City, Bryce Canyon National Park is another nearby national park that is reachable within a 1.5-hour drive. It’s famous for the eponymous Bryce Canyon, which is the national park’s main attraction.
This park boasts mesmerizing red rocks and pink cliffs that make up its spectacular hoodoos. Hikers love the several trails that lead to strategic viewpoints that offer an up-close look at Bryce Canyon’s wonders.
Capitol Reef National Park is found about 160 miles from Cedar City, a 2hr 45min drive. Visitors get to see the breathtaking red rocks that characterize this part of Utah. There are canyons and cliffs as well as the stunning Cathedral Valley.
Hiking is the main activity here, but tourists can also go horseback riding, mountain biking, rock climbing, and camping.
One of the world’s wonders, the Grand Canyon, is found 269 miles from Cedar City. This is a drive that will take about 4.5 hours. The park doesn’t just boast the massive canyon, it’s also home to a section of the Colorado River.
Visitors from Cedar City will access the Grand Canyon via the North Rim, but this side is usually closed in winter.
Cedar City is small; it’s only 36 square miles (93 square kilometers). So, there aren’t different neighborhoods as you’d find in bigger cities. Most of the accommodations are within the city center - here’s a list of some of the top-rated ones.
Cedar City is a haven for outdoorsy folks. So, the perfect day involves activities like hiking, biking, and kayaking.
The day would start with an all-American breakfast at one of the cafés in the downtown area. After the filling meal, head to Cedar Canyon Trail for an after-breakfast hike and a chance to get snippets of Utah’s scenery. This easy route takes about an hour to complete.
Afterward, visit Frontier Homestead State Park to learn about local history and explore the grounds. Then, have a picnic lunch at the park’s picnic spots.
Later cool off at the Cedar City Aquatic Center and enjoy a boating excursion at Lake at the Hills. Afterward, have dinner then catch a performance at the Beverley Taylor Sorensen Center for the Arts before ending the day with drinks at a local bar.
Yes, Cedar City is worth visiting for those who love outdoor activities like hiking, mountain biking, rock climbing, camping, and so much more. The city's proximity to Utah's national parks and other natural sights makes it a haven for nature lovers.
Cedar City is called Festival City because it hosts a number of Festivals throughout the year, including the popular annual Utah Shakespeare Festival.
Yes, Cedar City is just 60 miles from Zion National Park, which is about an hour's drive.
LOS ANGELES — Annette O'Toole is reveling in her “Virgin River” role as the unpredictable mayor of a small town whose woodsy, peaceful setting belies its residents’ roller-coaster lives.Her character is older but not always wiser, including in love. That goes against Hollywood’s tendency to view midlife-plus as past the sell-by date for nuanced storytelling, and O'Toole counts herself fortunate to play Hope McCrea.Make that doubly lucky. When the actor chose to stay with her 97-year-old mom ...
LOS ANGELES —
Annette O'Toole is reveling in her “Virgin River” role as the unpredictable mayor of a small town whose woodsy, peaceful setting belies its residents’ roller-coaster lives.
Her character is older but not always wiser, including in love. That goes against Hollywood’s tendency to view midlife-plus as past the sell-by date for nuanced storytelling, and O'Toole counts herself fortunate to play Hope McCrea.
Make that doubly lucky. When the actor chose to stay with her 97-year-old mom during the worst of the pandemic, that meant Hope was largely absent last season. The fourth and current season is a comeback for both, thanks to series creator Sue Tenney.
“She called me and said, ‘You’re in the hospital. You had a terrible car crash,” Tenney said of Hope’s in-limbo status. When O'Toole asked if Hope lives, Tenney let the actor decide: Did she want to return to the series, which stars Alexandra Breckenridge and is based on Robyn Carr’s novels?
“Are you kidding?” O'Toole replied. Such eagerness is characteristic, as proven by her resume that includes few gaps and some 100 film and TV credits (“Superman III,” “Nash Bridges” and “Smallville” among them). She earned an Emmy nomination for playing Rose Fitzgerald Kennedy in the 1990 miniseries “The Kennedys of Massachusetts,” a role she took on shortly after the birth of her second daughter.
She’s also emphasized theater work and, with husband Michael McKean, is a songwriter: several of their tunes were in “A Mighty Wind” — the film by McKean’s longtime friend and collaborator Christopher Guest — including the Oscar-nominated ballad “A Kiss at the End of the Rainbow.” Then there’s her Spinal Tap back-up singer bragging rights, most notably at a London benefit concert including actor-writer McKean, Guest and others in the faux band of satiric movie fame.
O'Toole, 70, was breezily good-natured in a phone interview with The Associated Press during season-five filming in Vancouver, which stands in for Northern California on “Virgin River.” There’s more “emotionally at stake” than ever and the town is “really going to be unified,” she said of next season.
There were no spoilers dropped, but O'Toole candidly discussed how her character is portrayed, Hope’s relationship with Doc Mullins, played by Tim Matheson, and the luck in finding the right partner in McKean, her second husband. Remarks were edited for clarity and brevity.
AP: ‘Virgin River’ isn’t sci-fi or fantasy, it’s simply human drama. Was that the appeal?
O'TOOLE: Exactly that. It’s about people and their issues and in a beautiful community. And Sue Tenney was so generous because this character is not really in the books very much, so we kind of had a blank slate to draw this person together. You don’t do it (a project) because you want it to be a big success. The chances of that happening are so slim. You do it because you want to, and you like the people. And at this point in my career it’s doing something that I haven’t quite done before. That’s why this character was attractive, because I could help form her into something a little more real than than a lot of the stuff I read for characters my age, grandmothers and the sweet kind of homebody. That’s boring, I’ve done that.
AP: What did you want to see in Hope instead?
O'TOOLE: I just wanted her to be complicated, a woman who even at her age doesn’t have the answers. She doesn’t have, at the beginning, a relationship that is steady. It’s very rocky. That’s interesting to me, somebody who has gone through most of her life and hasn’t figured it out yet. She’s impulsive and headstrong, and also very generous and can be very kind and loving. She’s just a person. I just wanted a full person.
AP: It’s a screen rarity for older characters to be shown other than in a long and loving marriage or widowed. Hope and Doc’s story isn’t the show’s central relationship, but it’s a focus.
O'TOOLE: How interesting that he was unfaithful early in their marriage and she cannot let him go. She never divorced him. She never said, well, that’s it. Tim is fantastic and we’ve come up with a whole full life that they’ve had together. It’s not been a normal marriage at all. The way we look at marriage, I love that marriage can be whatever you want it to be or not be.
AP: Hope is an attractive woman who doesn’t bother to hide her age behind hair dye or heavy makeup. Given the demands on women to be eternally youthful, how is to play a character who says, ‘Here I am world, an older woman?’
O'TOOLE: It’s wonderful. It’s the most fun I’ve ever had because when I started out, I was really young and I was sort of the ingenue, and then I was the leading lady in some things, and then you start to age. Now I just find it so freeing. I don’t worry about it, and that’s in life, too. So Hope and I feel the same way about it. It’s like, who are we trying to kid? Especially an actress, they can look you up (online) and see how old you are, see all the things you’ve done, look at all your pictures.
AP: You and Michael have been married for more than two decades, impressive for any couple and considered especially so in the entertainment industry.
O'TOOLE: We’re really good buddies. He just left, he’s been over in London doing another Netflix series, ‘The Diplomat.’ COVID was so terrible, but we were very lucky because it was the most consecutive days we had ever been together in our marriage. I realize we’re always saying goodbye. It was very hard because we’d been together so much, and we talked about the first time we said goodbye, and we talked about luck. We both really lucked out finding one another. I cannot imagine what my life without him, and he says the same thing about me.
Herbert "Skip" Virgin will lead work on translatability of scientific discoveries and translation to new medicines in collaboration with the three Institutes of Science at AltosSAN FRANCISCO, July 14, 2022 /PRNewswire/ -- Altos Labs (Altos) today announced that Herbert "Skip" Virgin, MD, PhD, will join the company as Chief Medical Officer and Head of the Altos Institute of Medicine, effective September 1, 2022. In his role, Dr. Virgin will lead work on the translatability of scientific discoveries and the tr...
Herbert "Skip" Virgin will lead work on translatability of scientific discoveries and translation to new medicines in collaboration with the three Institutes of Science at Altos
SAN FRANCISCO, July 14, 2022 /PRNewswire/ -- Altos Labs (Altos) today announced that Herbert "Skip" Virgin, MD, PhD, will join the company as Chief Medical Officer and Head of the Altos Institute of Medicine, effective September 1, 2022. In his role, Dr. Virgin will lead work on the translatability of scientific discoveries and the translation to transformative medicines in collaboration with the company's three Institutes of Science with the aim to restore cell health and reverse disease.
"Skip is a devoted, innovative scientist with an exceptional background in translational medicine, making him an ideal fit for Altos as we seek to reverse disease, injury, and disabilities using new approaches," said Altos Chief Scientist and Founder Rick Klausner. "As we unravel the deep biology of cellular rejuvenation programming, we also need to develop the means of translating that new understanding into medicines. We are honored that Skip has agreed to take on this challenge by leading the Altos Institute of Medicine."
Dr. Virgin currently serves as Executive Vice President, Research and Chief Scientific Officer at Vir Biotechnology, where he directed a team of more than 150 scientists focused on immune approaches to prevention and treatment of severe infectious disease. He is also an Adjunct Professor of Pathology and Immunology at Washington University School of Medicine and Adjunct Professor of Internal Medicine at UT Southwestern Medical Center.
"Altos is home to some of the most accomplished scientists in the fields of cell health and cellular rejuvenation programming, and I am excited by the opportunity to lead the Institute of Medicine to help translate this knowledge into transformative medicines," said Dr. Virgin. "Over my career, I've repeatedly encountered one of science's great mysteries: how and why different individuals facing the same disease experience widely variable severity and recovery. Understanding this process at the cellular level – and realizing the potential of that understanding to benefit humanity – is one of many reasons I decided to join Altos to support its efforts to harness cellular resilience."
Dr. Virgin has previously served as the Edward Mallinckrodt Professor and Chair of the Department of Pathology and Immunology at Washington University School of Medicine, the Director and Principal Investigator of the NIH-funded Midwest Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, and Director and Principal Investigator of an NIH-funded Center for Excellence in Translational Research. He is also an elected member of the National Academy of Sciences.
He holds AB, MD and PhD degrees from Harvard University and Harvard Medical School and trained clinically at Brigham and Women's Hospital and at Barnes Hospital.
About Altos Labs
Altos Labs is a new life sciences company focused on restoring cell health and resilience through cellular rejuvenation programming to reverse disease, injury, and the disabilities that occur throughout life. The company comprises a community of leading scientists, clinicians, and leaders from both academia and industry working together towards this common mission. Altos has operations in the San Francisco Bay Area, San Diego, and in Cambridge, UK, with significant collaborations in Japan.
Media ContactsMorgan WarnersFGS Global[email protected]
Kim JamesFGS Global[email protected]
SOURCE Altos Labs
Help reduce your risk of breast cancer with tips from an oncologist. For Breast Cancer Awareness Month, Jessica Trevino Jones, MD, oncologist and assistant professor with McGovern Medical School at UTHealth Houston, compiled the following researched tips to help reduce your risk! Before starting any new routine, speak with your physician.Skip morning meals!Try 16/8 intermittent fasting. Consume your meals from 11 a.m. to 7 p.m. (or noon to 8 p.m.) to help control your insuli...
Help reduce your risk of breast cancer with tips from an oncologist.
For Breast Cancer Awareness Month, Jessica Trevino Jones, MD, oncologist and assistant professor with McGovern Medical School at UTHealth Houston, compiled the following researched tips to help reduce your risk! Before starting any new routine, speak with your physician.
Try 16/8 intermittent fasting. Consume your meals from 11 a.m. to 7 p.m. (or noon to 8 p.m.) to help control your insulin and blood sugar levels — and weight! Eating your first meal late in the morning lowers the chances of breast cancer and cardiovascular disease!
Cook with extra virgin olive oil. This Mediterranean staple is rich in healthy fats and antioxidants. Eat a Mediterranean diet to further reduce your risk of breast cancer. High in plant-based foods and low in saturated meats, this diet better protects your body against disease.
Limit your alcoholic beverages. Seven or more glasses of wine a week can increase your threat of breast cancer by 50%. This is because excessive amounts of alcohol can alter hormone levels and promote cancer growth. Drink no more than four servings of alcohol a week.
Stay physically active. Women who engage in 30 minutes of brisk activity three times a week have a 12 to 21% lower risk of breast cancer than those who don’t. Anything that makes you break a sweat counts, whether it is biking, dancing, or mowing the lawn!
Lose excess weight now. As people age, weight gain can raise breast cancer risk. In addition to a healthy diet and exercise regimen, consider seeing a weight loss specialist to help lose any stubborn pounds. Consider weight loss medication, or, if necessary, surgery.
Get plenty of vitamin D. Low levels of this nutrient are linked to breast cancer as well as other cancers and degenerative diseases. Ask your doctor to check your vitamin D level to find out if you need more D-quenching sunshine and/or over-the-counter supplements.
Know your risk. Is your breast tissue dense? Do you have a family history of breast cancer? If the answers are “yes,” your odds increase more than 20%. Discuss the factors with your physician to see if you need dual screening (mammogram and MRI) each year.
Ask about medication. Taken daily, certain prescribed medications can reduce a person’s threat of breast cancer by up to 50% over a period of five years! If you run a higher probability, ask your doctor if you are eligible. Prevention is still the best medicine!
Jones is also the founder of the Breast Cancer Prevention program at UTHealth Houston. It offers consultation and care for women susceptible to breast cancer as well as genetic, nutrition, and weight loss counseling.
To schedule an appointment with the breast cancer team, call UT Physicians Multispecialty — Bayshore at 713-486-6325.
In early spring of 2021, when Rui Chen spotted eggs in petri dishes where she had treated virgin female schistosome flatworms with a compound she had just discovered in males, she thought she had made some sort of mistake – maybe she had accidentally dropped a few eggs into the dishes as well, since female schistosomes do not sexually mature or lay eggs except when clasped by males.James Collins, Ph.D., who heads t...
In early spring of 2021, when Rui Chen spotted eggs in petri dishes where she had treated virgin female schistosome flatworms with a compound she had just discovered in males, she thought she had made some sort of mistake – maybe she had accidentally dropped a few eggs into the dishes as well, since female schistosomes do not sexually mature or lay eggs except when clasped by males.
James Collins, Ph.D., who heads the UT Southwestern lab where Ms. Chen is a researcher and Ph.D. student, knew better. “You wouldn’t make a silly mistake like that; I think you’re on to something,” he told her.
So she repeated her experiment three more times, watching for egg production in the virgin worms after treating them with the synthetic compound her collaborators had helped her create in the lab after seeing it produced by males. “I saw the egg production again and again,” she said. Her findings were published this year in Cell, reporting the lab’s discovery of a pheromone, or excreted chemical, made by male schistosome worms that stimulates sexual maturation and egg-laying in females.
For her research, Ms. Chen received the 2022 Nominata Award, the highest honor for academic and research accomplishment bestowed by UT Southwestern’s Graduate School of Biomedical Sciences.
Ms. Chen’s hope is that these findings will one day lead to treatments that can prevent female schistosomes from laying the massive numbers of eggs that clog internal organs of those infected by the parasites. The parasitic disease schistosomiasis affects more than 200 million people in developing countries and leads to up to 200,000 deaths each year, according to the World Health Organization.
“Rui is not only a gifted experimentalist, but also a scholar with an uncanny sense of what the next experiment needs to be,” said Dr. Collins, Associate Professor of Pharmacology. “In the course of a single Ph.D., Rui has solved a problem I assumed I would struggle with my entire career.”
Ms. Chen was one of 10 nominees for the Nominata, established in 1980 by the Graduate Student Organization to promote academic excellence and research achievement at UT Southwestern. The winner receives a monetary award and presents their research to the UT Southwestern community, which Ms. Chen did on May 11.
Watch: Nominata Award winner Rui Chen
Two finalists received Dean’s Discretionary Awards: Abigail Watterson, a fourth-year Ph.D. student in Genetics, Development, and Disease who works in the lab of Peter Douglas, Ph.D., Assistant Professor of Molecular Biology; and Mahmoud Elguindy, Ph.D., a student in the Medical Scientist Training Program who works in the lab of Dr. Joshua Mendell, M.D., Ph.D, Professor of Molecular Biology, Howard Hughes Medical Institute Investigator, and member of the Harold C. Simmons Comprehensive Cancer Center. Dr. Elguindy expects to receive his medical degree in May 2023.
Ms. Chen was born and reared in Wuhan, China, one of the countries in Asia and sub-Saharan Africa with a history of the chronic and sometimes fatal disease caused by schistosomes. She had heard of the parasitic disease growing up, she said, but it had become less of a problem by then due to the country’s efforts to eradicate it.
She earned a Bachelor of Science in basic biology from Wuhan University and completed an eight-month laboratory internship at UT Southwestern during her senior year of college before deciding to seek a Ph.D. in cell and molecular biology here. Ms. Chen expects to complete her Ph.D. this year.
She was drawn to Dr. Collins’ research into the biology of schistosomes because learning more about their sexual processes could help in the development of treatments for a disease that leads to disability and death in so many of the world’s poorest inhabitants – as well as because she was fascinated by the worm’s unusual reproductive process. They are the only type of flatworms that come in both male and female sexes rather than being hermaphrodites, and the male must hold the female next to him constantly within a long pouch on his body for her to become and remain sexually mature and lay eggs.
Schistosome infection occurs when people come into contact with the worm’s tiny, grain-of-sand-sized larvae in contaminated water. Once the larvae pass through the skin, they enter blood vessels, where they feed and grow over a few weeks into half-inch-long worms, Ms. Chen said.
But it is the females’ huge number of eggs – not the worms themselves – that creates the biggest problem, she said. “They lay eggs constantly after they reach sexual maturation,” Ms. Chen said. These masses of worm eggs get stuck in the organs of those infected such as the spleen and liver and lead to an immune response that can cause sickness. Abdominal pain and diarrhea are early symptoms, with enlargement of the liver and spleen in advanced cases, according to WHO.
Treatment involves killing the adult worms with the drug praziquantel, Ms. Chen said, but that doesn’t remove eggs stuck in organs and treatment must be repeated as more larvae reach adulthood or reinfection occurs.
Preventing the females from reaching sexual maturity and laying eggs – which they do only after pairing with a male – could provide a better solution, Ms. Chen said.
Understanding how schistosomes’ male-induced sexual maturity works could lead to drugs that prevent the release of BATT from the males or its effect on females, she said. Ms. Chen said another graduate student in the Collins lab is trying to locate the BATT receptor that takes up the chemical in females, while Ms. Chen tests BATT-like chemicals that might block BATT or the receptors for it.